如何预测lncRNA/sncRNA的靶基因

如何预测lncRNA/sncRNA的靶基因

How to predict target of lncRNA/sncRNA

       除了微小RNA（miRNA），长链非编码RNA（lncRNA）和小非编码RNA（sncRNA）还可通过与其他靶标（包括mRNA，rRNA和sncRNA）互作发挥作用。因此，靶基因预测对于lncRNA/sncRNA的研究十分重要。本文将讲解如何预测lncRNA/sncRNA的靶基因。

Except micro RNA (miRNA), long non-coding RNA (lncRNA) and small non-coding RNA (sncRNA) also exert their functions by interacting with other targets, including mRNA, rRNA and sncRNA. Therefore, target prediction is critical for studying lncRNA/sncRNA.

对于已知的lncRNA/sncRNA，可以通过ENCORI/Starbase预测靶基因：

For known lncRNA/sncRNA, targets could be predicted by ENCORI/Starbase:

1从https://rnasysu.com/encori/index.php网址进入ENCORI/Starbase

1 Enter ENCORI/Starbase from https://rnasysu.com/encori/index.php

2 点击RNA-RNA，选择lncRNA/sncRNA-mRNA

2 Click RNA-RNA，select lncRNA/sncRNA-mRNA

3选择物种

3 Select a species

4输入lncRNA/sncRNA名称，快速搜索

4 Enter the lncRNA/sncRNA name, quick search

5查看结果

5 View results

对于新发现的lncRNA，靶基因预测步骤如下：

For novel lncRNA, the steps of target prediction are as follows:

1从http://www.cuilab.cn/lnctar网址进入LncTar

1 Enter LncTar from http://www.cuilab.cn/lnctar

2点击Prediction

2 Click Prediction

3输入lncRNA与潜在靶基因序列，提交

3 Enter sequences of lncRNA and potential target, Submit

4查看结果

4 View results